Total ankle replacement with antibiotic-impregnated cement: a case report on the infected ankle management

Authors

  • Reyanne N. Strong University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA https://orcid.org/0009-0008-9705-2881
  • Abigail E. Smith University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
  • Nathaniel T. Koutlas University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
  • James O. Sanders University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
  • Trapper Lalli University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA https://orcid.org/0000-0001-8357-0428

DOI:

https://doi.org/10.30795/jfootankle.2025.v19.1846

Keywords:

Arthroplasty, replacement, ankle; Arthritis, reactive; Antibiotic prophylaxis; Bone cements.

Abstract

Ankle fracture infection is a devastating complication that can lead to chronic pain, limited motion, post-infectious end-stage ankle
arthritis, osteomyelitis, and amputation. Treatment historically involves aggressive debridement, hardware removal, and long-term
antibiotic therapy. We describe a case of post-infectious end-stage ankle arthritis treated with a custom, fixed-bearing, 3D printed total
ankle replacement with antibiotic-impregnated cement. The provided treatment allows continued elution of high-dose local antibiotics
while preserving the ankle range of motion and allowing immediate weight bearing postoperatively. Level of evidence V; Therapeutic studies; Expert opinion.

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Published

2025-04-15

How to Cite

Strong, R. N., Smith, A. E., Koutlas, N. T., Sanders, J. O., & Lalli, T. (2025). Total ankle replacement with antibiotic-impregnated cement: a case report on the infected ankle management. Journal of the Foot & Ankle, 19(1), 1–5. https://doi.org/10.30795/jfootankle.2025.v19.1846